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Referenz | 9DFE04D8 |
Bereich | Life Science - Pharma - Chemie |
Position | MSc Bioanalytics |
In Kürze | Liposomes & rhabdomyosarcoma |
Kompetenzen | Developed drug-loaded liposomes for the synergistic chemotherapy of rhabdomyosarcoma • Formulated and characterized DSPC-Chol-PEG liposomes loaded with vincristine (VCR) and actinomycin d (dAct), either individually or coencapsulated • Evaluated encapsulation efficiency, drug loading, mean diameter, polydispersity index, and zeta potential of liposomes. • Performed in vitro evaluation on RMS cell lines (RD, Rh30, and Rh4) to assess cytotoxicity and determine IC50 values • A key achievement was identifying concentration-dependent synergy in drug treatments Techniques: - Mammalian Cell Culture - Cell Viability Assays . Drug Loading in Liposomes - PCR - RNA Isolation - Fluorescence Microscopy - Confocal Microscopy - Gel Electrophorensis - HPLC - DLS |
Sprachen | Schweizerdeutsch: Muttersprache Deutsch: Muttersprache Englisch: Fliessend in Wort und Schrift |
Pensum | 100% |
Jahrgang | 28 Jahre alt |
Verfügbarkeit | per sofort oder nach Vereinbarung |